Tangri, N., Ferguson, T., Wiebe, C., Eng, F., Nash, M., Astor, B., Lam, N., Ye, F., Shin, J., Whitlock, R., Yuen, D.
Canadian Journal of Kidney Health and DiseasePublication Category Read More
Predicting allograft failure in kidney transplant recipients can help plan renal replacement therapy and guide patient-provider communication. The kidney failure risk equation (KFRE) accurately predicts the need for dialysis in patients with chronic kidney disease (CKD), but has not been validated in kidney transplant recipients. We sought to validate the 4-variable KFRE (age, sex, estimated glomerular filtration rate [eGFR], and urine albumin-to-creatinine ratio [ACR]) for prediction of 2- and 5-year death-censored allograft failure.
Acute Kidney Injury Events in Patients With Type 2 Diabetes Using SGLT2 Inhibitors Versus Other Glucose-Lowering Drugs: A Retrospective Cohort Study
Rampersad, C., Kraut, E., Whitlock, R., Komenda, P., Woo, V., Rigatto, C., Tangri, N.
American Journal of Kidney DiseasesPublication Category Read More
Sodium glucose cotransporter 2 (SGLT2) inhibitors slow the progression of chronic kidney disease and prevent heart failure events. However, SGLT2 inhibitors may increase the risk of acute kidney injury (AKI). Our objective was to assess whether SGLT2 inhibitor use, compared to all other glucose lowering drugs (oGLD), is associated with increased rates of AKI.
Rampersad, C., Whitlock, R., Leslie, W., Rigatto, C., Komenda, P., Bohm, C., Hans, D., Tangri, N.
Osteoporosis InternationalPublication Category Read More
We sought to determine whether trabecular bone score (TBS) either independently or adjusted for The Fracture Risk Assessment Tool (FRAX) could predict risk of major osteoporotic fractures (MOFs) in a large population-based sample of patients with all stages of chronic kidney disease (CKD).