Publications

Seven Oaks Hospital has developed a rich culture of curiosity, ideation, and the collective determination to discover and deploy better ways of doing things. Today, world-leading researchers are drawn to the Seven Oaks Hospital community of innovation, and the momentum continues to build.

Publication

Validation of the Kidney Failure Risk Equation in Kidney Transplant Recipients

Tangri, N., Ferguson, T., Wiebe, C., Eng, F., Nash, M., Astor, B., Lam, N., Ye, F., Shin, J., Whitlock, R., Yuen, D.

Canadian Journal of Kidney Health and Disease

Publication Category

Study Description

Predicting allograft failure in kidney transplant recipients can help plan renal replacement therapy and guide patient-provider communication. The kidney failure risk equation (KFRE) accurately predicts the need for dialysis in patients with chronic kidney disease (CKD), but has not been validated in kidney transplant recipients. We sought to validate the 4-variable KFRE (age, sex, estimated glomerular filtration rate [eGFR], and urine albumin-to-creatinine ratio [ACR]) for prediction of 2- and 5-year death-censored allograft failure.

Publication

Acute Kidney Injury Events in Patients With Type 2 Diabetes Using SGLT2 Inhibitors Versus Other Glucose-Lowering Drugs: A Retrospective Cohort Study

Rampersad, C., Kraut, E., Whitlock, R., Komenda, P., Woo, V., Rigatto, C., Tangri, N.

American Journal of Kidney Diseases

Publication Category

Study Description

Sodium glucose cotransporter 2 (SGLT2) inhibitors slow the progression of chronic kidney disease and prevent heart failure events. However, SGLT2 inhibitors may increase the risk of acute kidney injury (AKI). Our objective was to assess whether SGLT2 inhibitor use, compared to all other glucose lowering drugs (oGLD), is associated with increased rates of AKI.

Publication

Trabecular bone score in patients with chronic kidney disease

Rampersad, C., Whitlock, R., Leslie, W., Rigatto, C., Komenda, P., Bohm, C., Hans, D., Tangri, N.

Osteoporosis International

Publication Category

Study Description

We sought to determine whether trabecular bone score (TBS) either independently or adjusted for The Fracture Risk Assessment Tool (FRAX) could predict risk of major osteoporotic fractures (MOFs) in a large population-based sample of patients with all stages of chronic kidney disease (CKD).

Research Division · Seven Oaks Chronic Disease Innovation Centre
2300 McPhillips Street · Winnipeg, Manitoba · R2V 3M3 · 204‑631‑3834