Research

Applying the Kidney Failure Risk Equation

Incidence of age and lifestyle-related chronic disease in Canada continues to rise. The result is an ever-increasing burden on our health care systems and reduced quality of life for those living with illness. One example is Chronic Kidney Disease (CKD) which affects 3.1 million, or 11% of Canadian adults. In Manitoba 15% of adults have CKD, the highest in Canada.

The Kidney Failure Risk Equation Study by researcher Dr. Navdeep Tangri and his colleagues at CDIC has led to the development of a simple and reliable tool that is used with patients who have kidney disease. The Kidney Failure Risk Equation accurately predicts which patients are at risk of kidney failure.

Dr. Tangri’s study of several thousand Canadian patient health records resulted in an algorithm, published in the Journal of the American Medical Association that used eight common lab tests to accurately predict a two and five year risk of kidney failure. Seven Oaks Hospital has been using the equation since 2011 to identify high-risk patients who need to see a specialist vs. low-risk patients who can be managed by their family physicians.

Now, a new study by Dr. Tangri and other international researchers using 700,000 patient records from 30 countries has simplified the equation and confirmed that it is applicable to kidney patients globally. The equation is now a global standard for predicting kidney failure. CDIC researchers have created online tools to help family physicians use the Kidney Failure Risk Equation with their patients. Now researchers are applying the same process to create better risk equations for other diseases

Research Division · Seven Oaks Chronic Disease Innovation Centre
2300 McPhillips Street · Winnipeg, Manitoba · R2V 3M3 · 204‑631‑3834